chromatin remodeling

소개글

chromatin remodeling에 대한 발표 자료(ppt)입니다
참고한 논문은annual review of biochemistry입니다.

목차

INTRODUCTION
1. ATP-dependent Chromatin Remodeling Complex
2. Classification And Subunit Composition
3. Mechanism of ATP-dependent Chromatin Remodeling Complex
Summary

본문내용

INTRODUCTION

The fate of the cell relies on a delicate balance between gene expression and repression.


The nucleosome can be restructured by two mechanisms:

1. the modification of core histones by histone acetyltransferases, deactylases, methyltrans-ferases, and kinases.

2. the movement of nucleosomes along DNA which is carried out by ATP-dependent chromatin remodeling complexes;


The purpose of the chromatin remodeling proteins is to alter the nucleosome architecture such that genes are exposed to or hidden from the transcriptional machinery.

참고 자료

Caroline Demeret1,2, Yegor Vassetzky1 and Marcel Me