유방암 진단과 치료

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1. Epidemiology
1) Incidence rate : 111 cases per 100,000 woman-years (wy) in 1996.( the most frequently diagnosed cancer in American women. )
Mortality rate : 24 deaths per 100,000 wy,( the second leading cause of cancer death in American women )
In recent years : slight overall decline in breast cancer age-adjusted mortality, in contrast to pronounced peaks in incidence.
80% to 92% of all breast masses are benign. Approximately 1% of breast cancers occur in men.
2) risk factors
age greater than 50 years,
personal or family history of breast cancer(e.g., mother, aunt)
nulliparous, or first child after 30 years of age

2. Natural History
1) site of origin of breast cancer : upper outer quadrant (38.5%)
central area (29%)
upper inner quadrant (14.2%),
lower outer quadrant (8.8%)
lower inner quadrant (5%).
2) more common in the left than in the right breast

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