분자생물학 기말 레포트

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"분자생물학 기말 레포트"에 대한 내용입니다.

목차

1. Abstract
2. Introduction
3. Materials and Methods
4. Results
5. References

본문내용

Abstract
TLR은 innate immune에 중요한 역할을 하며 DC등의 immune cell에 광범위하게 분포하고 있다. DC는 antigen을 presenting하며 이것을 통해 T cell을 활성화시켜 adaptive immune response에 관여한다. A20은 다양한 면역반응의 inhibitor이다. A20-silenced DC는 anti-HIV 면역반응을 일으키는데 탁월한 능력이 있어서 vaccination에 활용될 수 있다.

Introduction
인간에게는 크게 두 가지 면역체계가 있다. 첫 번째는 감염이 일어났을 때 신속하게 일어나는 innate immunity가 있고 두 번째는 뒤이어서 천천히 일어나는 adaptive immunity가 있다. Innate immunity가 신속하지만 specificity가 떨어지는 반면 adaptive immunity는 그것을 유발한 antigen에 매우 specific하게 작용하며 오랜 기간 해당 antigen에 다시 노출되었을 때 신속하게 대응할 수 있는 memory기능이 있다.

참고 자료

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