[화학실험] 아스피린 합성 pre-report (예비레포트)
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- 2016.06.13
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소개글
아스피린 합성 예비레포트 입니다.
영문으로 작성되어있습니다.
목차
1. Theory & Summary
2. Chemical information
3. Procedure
4. Prelab exercises
Reference
본문내용
1. Theory & Summary
-Aspirin
Aspirin, known as acetylsalicylic acid, is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.
Aspirin was the first discovered member of the class of drugs known as non-steroidal anti-inflammatory drugs, not all of which are salicylates, although they all have similar effects and most have inhibition of the enzyme cyclooxygenase as their mechanism of action. Today, aspirin is one of the most widely used medications in the world, with an estimated 40,000 metric tons of it being consumed each year. In countries where Aspirin is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid.
-The synthesis of aspirin
The synthesis of aspirin is classified as an esterification reaction. Salicylic acid is treated with acetic anhydride, an acid derivative, causing a chemical reaction that turns salicylic acid's phenol group into an acetyl group, (R-OH -> R-OCOCH3).
참고 자료
http://100.naver.com/100.nhn?docid=134121
http://100.naver.com/100.nhn?docid=117139
http://en.wikipedia.org/wiki/Aspirin
http://en.wikipedia.org/wiki/Salicylic acid
http://en.wikipedia.org/wiki/Acetic anhydride
http://en.wikipedia.org/wiki/Phosphoric acid
http://en.wikipedia.org/wiki/Petroleum ether
http://en.wikipedia.org/wiki/Diethyl ether
http://blog.naver.com/evanlune?Redirect=Log&logNo=70040531290
http://kin.naver.com/detail/detail.php?d1id=7&dir_id=707&eid=bOaGUwursxm7xn1kupmfmDXdfAqg7Nld&qb=7JWE7Iqk7ZS866aw7ZWp7ISx&enc=utf8
http://kin.naver.com/detail/detail.php?d1id=11&dir_id=110204&eid=SMbVhEIEDc+GWKe5aEkSvWZUXyQakxlQ&qb=vsa9usfHuLDH1by6&enc=euc-kr
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