Neural crest & Fibroblast growth factors & Transforming growth factors in development
- 최초 등록일
- 2015.08.25
- 최종 저작일
- 2014.12
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한컴오피스
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목차
1. Roles of Fibroblast Growth Factors in development
2. Roles of Transforming Growth Factors in development
3. Neural crest cells in development
Reference
본문내용
FGFs make a family of polypeptide that are found in organisms ranging from nematodes to humans. In vertebrates, the 22 members of the FGF family range in molecular mass from 17 to 34 kDa and share 13-71% amino acid identity. During embryonic development, FGFs have diverse roles in regulating cell proliferation, migration and differentiation. A subset of the FGF family, expressed in adult tissue, is important for neuronal signal transduction in the central and peripheral nervous systems.
<중 략>
-Although derived from the ectoderm, the neural crest has sometimes been called the fourth germ layer because of its importance.
-The neural crest cells originate at the dorsalmost region of the neural tube. -Transplantation experiments wherein a quail neural plate is grafted into a chick non-neural ectoderm have shown that juxtaposing these tissues induces the formation of neural crest cells, and that both the prospective neural plate and the prospective epidermis contribute to the neural crest.
참고 자료
Aimin Liu, Charlotte Wang, Lee Niswander (2005), Fibroblast Growth Factors in Development, eLS, 2005 May;DOI: 10.1038/npg.els.0003306
Nobuyuki Itoh, David M Ornitz (2010), Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease, Japanese. Biochemical society. 2011;149(2):121130
David M Ornitz, Nobuyuki Itoh (2001), Protein family review; Fibroblast growth factors, Genome Biology 2001, 2(3):reviews 3005.1-3005.12
Gail R. Martin (1988), The roles of FGFs in the early development of vertebrate limbs, GENES & DEVELOPMENT 12:1571–1586
Transforming growth factor-beta : a general review : Lawrence DA, Eur cytokine Nets. 1996 Sep;7 (3): 363-74
Human Embryology and Developmental Biology, 5th Edition / Chapter 12 Neural crest
Larsen’s Human Embryology (4th ed.). Chapter 10, 16
Developmental Biology. 6th edition.
Hill, M.A. (2014). UNSW Embryology (14th ed.) Retrieved December 14, 2014
Moore, K.L. & Persuad, T.V.N. (2008). The Developing Human: clinically oriented embryology (8th ed.). Philadelphia: Saunders. /chapter 9, 17
tree : http://discovery.lifemapsc.com/in-vivo-development/neural-crest
