토가바이러스와 플라비바이러스 (Togaviruses and Flaviviruses)

소개글

토가바이러스와 플라비바이러스 (Togaviruses and Flaviviruses)

목차

Alphaviruses and Flaviviruses
Flaviviruses
일본뇌염 (Japanese B encephalitis)
Clinical features
황열 (Yellow fever)
뎅기열 (Dengue fever)
West Nile virus
Togaviruses
풍진 (Rubella, German measles)
선천성 풍진 (Congenital rubella syndrome)

본문내용

Arboviruses - spread by arthropod vector
Very broad host range
: vertebrate and invertebrate(mosquito, ticks)
Zoonoses - viruses spread by animals or with an animal reservoir

Structure and replication of Alphaviruses

Shape: icosahedral capsid
Size: Alphavirus(45-75nm in diameter)
Genome: (+) ssRNA
Enveloped virus: obtained from host cell membranes
Structural protein of Alphavirus
: capsid protein(C), glycoprotein(E1, E2)
Structural protein of Flavivirus
: E protein -glycoprotein in envelop
: M protein - envelop protein
: C protein - nucleocapsid protein

참고 자료

없음