Synthesis of heteroatoms doped reduced graphene oxide for the electrochemical determination of uric acid in commercial milk
* 본 문서는 배포용으로 복사 및 편집이 불가합니다.
서지정보
ㆍ발행기관 : 한국탄소학회
ㆍ수록지정보 : Carbon letters / 33권 / 7호
ㆍ저자명 : Fatma Besbes, Zouhour Hsine, Rym Mlika
ㆍ저자명 : Fatma Besbes, Zouhour Hsine, Rym Mlika
목차
Synthesis of heteroatoms doped reduced graphene oxide for the electrochemical determination of uric acid in commercial milkAbstract
Graphical Abstract
1 Introduction
2 Materials and methods
2.1 Reagent and solution
2.2 Apparatus
2.2.1 Fourier-transformed infrared spectroscopy (FTIR)
2.2.2 Raman spectroscopy (Raman)
2.2.3 X-ray Photoelectron Spectrometer (XPS)
2.2.4 Sessile drop method (contact angle measurements)
2.2.5 Electrochemical measurements
2.3 Hydrothermal synthesis of N-RGO and S-RGO
2.4 Electrode modifications
2.5 Real sample preparation
3 Results and discussion
3.1 Chemical and surface characterization of S-RGO and N-RGO
3.1.1 FTIR spectroscopy
3.1.2 Raman spectroscopy
3.1.3 XPS characterization
3.1.4 Wettability tests
3.2 Electrochemical characterization
3.2.1 Cyclic voltammetry analysis
3.2.2 Electrochemical impedance spectroscopy analysis
3.3 Uric acid detection
3.3.1 Individual determination of UA on different electrodes
3.3.2 Electrochemical activities of UA in presence of XA
3.3.3 Simultaneous determination of UA at N-RGOSPCE
3.3.4 Interferences
4 Sensitivity, repeatability, and reproducibility of the N-RGOSPCE electrochemical biosensor
5 Determination of UA in real sample (milk sample)
5.1 Real application in 100-time diluted milk
5.2 Real application in 10-time diluted milk
5.3 Comparison
6 Conclusions
Acknowledgements
References
영어 초록
A simple and one-pot synthetic procedure using two different sources has been demonstrated to prepare heteroatoms doped reduced graphene oxide such as nitrogen-doped reduced graphene oxide (N-RGO) and sulfur-doped reduced graphene oxide (S-RGO). The N-RGO has been hydrothermally synthesized using urea as nitrogen precursor, wherein the S-RGO has been synthesized using dimethyl sulfoxide (DMSO) as sulfur precursor. The successful N-doping, S-doping and other physicochemical properties of N-RGO and S-RGO have been confirmed with different spectroscopic and electrochemical techniques. The results indicated that doping into the graphene structure exhibits a high conductivity and a better transfer of charge. Moreover, heteroatoms doped graphene (N-RGO and S-RGO) and graphene-related materials (RGO) have been applied for the individual detection of uric acid (UA). Interestingly, the N-RGO exhibited a lower limit of detection (LOD, S/N = 3) of 2.7 10– 5 M for UA (10–1000 μM) compared with undoped RGO and S-RGO. Furthermore, the simultaneous detection of UA in the presence of Xanthine (XA) has been demonstrated a wide linear range of detection for UA: 10–1000 μM, with unchanged concentration of XA to be 200 μM, and exhibited a low limit of detection of 8.7 10− 5 M ( S∕N = 3) for UA. This modified sensor based on N-RGO has revealed a high selectivity and reproducibility thanks to its large surface area, high catalytic properties, and chemical structure. Indeed, the practical applicability of the proposed sensor has been evaluated in milk samples even in the presence of high concentrations of UA with satisfactory results.참고 자료
없음"Carbon letters"의 다른 논문
- Interdependent factors influencing the carbon yield, st..13페이지
- Experiment and molecular simulation for liquid phase ad..15페이지
- Black phosphorus nanosheets‑based effective electrochem..9페이지
- Preparation and effect evaluation of rigid polyurethane..9페이지
- Fabrication of graphene‑assisted voltammetry platform f..10페이지
- A sandwich‑like CMC‑based/graphene/CMC‑based conductive..15페이지
- In‑situ growth of ZIF‑8/CP with ultra‑high adsorption c..11페이지
- A comparative study on metal species implanted amine–br..11페이지
- Investigation on thermal conductivity of dimethyl silic..7페이지
- Predicting the wear performance of graphene and silicon..26페이지