광주 거주자의 타액 검사와 혈액 검사의 비교 고찰

서지정보

ㆍ발행기관 : 대한구강악안면병리학회 ㆍ수록지정보 : 대한구강악안면병리학회지 / 35권 / 2호
ㆍ저자명 : 조성훈, 김서연, 고영종, 임원봉, 오미라, 김지선, 김인애, 권혁일, Sandeep Karna, 김옥준, 최홍란

목차

I. INTRODUCTION
II. MATERIALS AND METHODS
1. Population and Saliva
2. Blood chemistry
3. Enzyme-linked immunosorbent assays (ELISA)
4. Statistical analysis
III. RESULTS
1. Properties of participants
2. Correlation of salivary ALT with serum ALT
3. Correlation of salivary AST with serum AST
4. Correlation of salivary cholesterol withserum cholesterol
5. Correlation of salivary triglyceride withserum triglyceride
6. Correlation of salivary albumin with serumalbumin
7. Correlation of salivary γ-GTP with serumγ-GTP
IV. DISCUSSION
V. CONCLUSIONS
VI. REFERENCES

영어 초록

A blood test is a laboratory analysis performed on a blood sample that is usually extracted from a vein in the arm using a needle, or via fingerprick. They are used to determine physiological and biochemical states, such as disease, mineral contents, drug effectiveness, and organ function. Although the term blood test is used, most routine tests (except for most haematology) are done on plasma or serum, instead of blood cells. Main advantage of using saliva in diagnostics is easy and non invasive sample taking compared to peripheral blood. According to the study published, saliva contains more than 20 percent of the proteins found in blood. The purpose of present study is to compare biochemical enzymes in saliva and in blood serum and to evaluate the usefulness of saliva specimens instead of blood in dental clinic. The saliva from 215 healthy over 50 years of aged people lived in Dong-gu district, Gwangu city was collected and the analysis was performed by six enzyme-linked immunosorbent assays (ELISA). ELISA results were compared with blood chemistry results. The values or patterns on Alanine Aminotransperase (ALT), Aspartate Aminotransperase (AST), Cholesterol and Triglyceride in saliva were not correlated with those in blood serum. However, Albumine and γ-glutamyl transpeptidase (γ-GTP) were followed the positive relationship with blood chemistry. These result showed that detection and identification of Albumine and γ-GTP level could be established by saliva ELISA analysis, so that ELISA assay on saliva could be useful alternative to serum testing.

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